What is the 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide?

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide is , while it's Molecular Formula is C12H17 O3 P. Used in Neurodegenerative Disease Research: TBO is utilized as a fluorescent dye for selectively staining amyloid deposits in tissue samples. This application is crucial for the study of Alzheimer's disease and other neurodegenerative conditions, aiding researchers in visualizing and analyzing the presence and distribution of amyloid plaques, which are a hallmark of these diseases. Used in Optical Sensors Development: In the field of sensor technology, TBO is employed in the development of optical sensors. Its fluorescent properties allow for the sensitive detection of specific molecules or conditions, making it a valuable component in creating advanced sensor systems for various analytical and diagnostic purposes. Used in Fluorescence Microscopy: TBO is also used in fluorescence microscopy as a staining agent. Its ability to produce a strong fluorescent signal upon binding to specific targets makes it an effective tool for imaging cellular and molecular structures, enhancing the visualization of biological samples and contributing to a deeper understanding of biological processes. Used in Pharmaceutical Research: Although not explicitly mentioned in the provided materials, TBO's properties may also make it a candidate for use in pharmaceutical research, particularly in the development of drugs targeting amyloid-related diseases. Its selectivity for amyloid deposits could potentially be leveraged in the design of drugs that aim to modulate or clear these structures, offering new therapeutic strategies for treating neurodegenerative conditions.

What is the 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide?

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide is , while it's Molecular Formula is C12H17 O3 P. Used in Neurodegenerative Disease Research: TBO is utilized as a fluorescent dye for selectively staining amyloid deposits in tissue samples. This application is crucial for the study of Alzheimer's disease and other neurodegenerative conditions, aiding researchers in visualizing and analyzing the presence and distribution of amyloid plaques, which are a hallmark of these diseases. Used in Optical Sensors Development: In the field of sensor technology, TBO is employed in the development of optical sensors. Its fluorescent properties allow for the sensitive detection of specific molecules or conditions, making it a valuable component in creating advanced sensor systems for various analytical and diagnostic purposes. Used in Fluorescence Microscopy: TBO is also used in fluorescence microscopy as a staining agent. Its ability to produce a strong fluorescent signal upon binding to specific targets makes it an effective tool for imaging cellular and molecular structures, enhancing the visualization of biological samples and contributing to a deeper understanding of biological processes. Used in Pharmaceutical Research: Although not explicitly mentioned in the provided materials, TBO's properties may also make it a candidate for use in pharmaceutical research, particularly in the development of drugs targeting amyloid-related diseases. Its selectivity for amyloid deposits could potentially be leveraged in the design of drugs that aim to modulate or clear these structures, offering new therapeutic strategies for treating neurodegenerative conditions.

Home > Organic Chemicals

Organic Chemicals

Product classification

Contact us

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide

Q: What is the CAS number for 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide?

The CAS number of 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide is 15761-96-3.

Q: What is 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide (15761-96-3) used for?

2-Benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide, commonly referred to as TBO, is a phosphorinane compound characterized by its fluorescent properties. It is recognized for its unique ability to selectively stain amyloid deposits in tissue samples, which is particularly valuable in the study of Alzheimer's disease and other neurodegenerative conditions. TBO's stability and non-toxic nature make it a versatile compound for various applications in research and medical diagnostics.InChI:InChI=1/C12H17O3P/c1-12(2)9-14-16(13,15-10-12)8-11-6-4-3-5-7-11/h3-7H,8-10H2,1-2H3

CAS：15761-96-3
purity：99%

Inquiry

Factory supply 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide 15761-96-3 with low price

Molecular Formula: C12H17 O3 P
Molecular Weight: 240.239
Vapor Pressure: 0.000202mmHg at 25°C
Boiling Point: 337.7°Cat760mmHg
Flash Point: 171.7°C
PSA： 45.34000
Density: 1.15g/cm³
LogP: 3.45270

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide(Cas 15761-96-3) Usage

General Description

2-Benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide, also known as TBO, is a phosphorinane compound that is used as a fluorescent dye in biological and chemical research. It is known for its ability to selectively stain amyloid deposits in tissue samples, making it a powerful tool for studying Alzheimer's disease and other neurodegenerative conditions. TBO is also used in the development of optical sensors and in fluorescence microscopy. It is considered to be a relatively stable and non-toxic compound, making it suitable for a wide range of applications in research and medical diagnostics.

InChI:InChI=1/C12H17O3P/c1-12(2)9-14-16(13,15-10-12)8-11-6-4-3-5-7-11/h3-7H,8-10H2,1-2H3

15761-96-3 Relevant articles

Studies on the efficient generation of phosphorus-carbon bonds via a rearrangement of PIII esters catalysed by trimethylhalosilanes

Dabkowski, Wojciech,Ozarek, Alfred,Olejniczak, Sebastian,Cypryk, Marek,Chojnowski, Julian,Michalski, Jan

experimental part, p. 1747 - 1756 (2009/09/25)

Halotrimethylsilanes Me3SiX (X = Br, I) ...

15761-96-3 Process route

: 2-benzyloxy-5,5-dimethyl-1,3,2-dioxaphosphorinane

: 15761-96-3
2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-one

Conditions

Conditions	Yield
With trimethylsilyl bromide; at 80 ℃; Inert atmosphere;	90%

: 1005-69-2
2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane

: 100-44-7
benzyl chloride

: 15761-96-3
2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-one

Conditions

Conditions	Yield
at 170 - 180 ℃;

15761-96-3 Upstream products

1005-69-2
2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane
100-44-7
benzyl chloride
126-30-7
2,2-Dimethyl-1,3-propanediol

MESOTARTARIC ACID

1-(2-methylnaphthyl)-1H-pyrrole-2,5-dione

5-Aminofluorescein

2,4,4,7-tetramethylnona-6,8-dien-3-one oxime

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide

Home

Company Introduction

Product Center

Organic Chemicals

Agrochemicals

Pharmaceutical

Food Additives

Others

Industry News

Contact Us

Organic Chemicals

Product classification

Contact us

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide

Factory supply 2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide 15761-96-3 with low price

2-benzyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide(Cas 15761-96-3) Usage

15761-96-3 Relevant articles

Studies on the efficient generation of phosphorus-carbon bonds via a rearrangement of PIII esters catalysed by trimethylhalosilanes

Dabkowski, Wojciech,Ozarek, Alfred,Olejniczak, Sebastian,Cypryk, Marek,Chojnowski, Julian,Michalski, Jan

experimental part, p. 1747 - 1756 (2009/09/25)

15761-96-3 Process route

15761-96-3 Upstream products

Related products